You may need to put aside your political preferences for a moment to read this worthwhile article from Wired about how charities are picking up on the grass-roots fund raising success of Moveon.org and the Howard Dean campaign to increase success in online fundraising.
Many charities now focus on building relationships with their supporters. They’re using e-mail lists to solicit donations and mobilize support. They run educational campaigns through e-mail to keep their community informed. They even arrange “meet-ups” offline to keep supporters involved.
Michael Gilbert, who publishes Nonprofit Online News, said groups are using the Web to build personal relationships, so supporters have a close connection with their pet causes.
Sounds pretty CRM-ish to me.